RELEVANCE OF PHARMACOGEOMICS IN OVARIAN STIMULATION : A REVIEW

Genetic polymorphism is defined as the detection of a single genetic mutation in humans, and addition each allele should occur at rate least 1% population. Potential strategies for detecting various alleles related to specific diseases or responses drug treatment include case-control studies uninvolved affected individuals genome scanning techniques.Tailoring ovarian stimulation individual patient can be challenging because response varies substantially between patients. Pharmacogenetics has emerged new area research improve balance desired undesired actions drugs, based upon predisposition patient. In summary, use genomic techniques may not limited rapid complete drugs. The Ser680 gene FSH-receptor been shown cause low resistance FSH action homozygous women (Ser680 / Ser680). potential role AMH influencing stimulation. Estrogen plays an important development secondary sex, fetal growth, reproductive cycle, maintenance pregnancy.